The parties also agree, without further consideration, to execute such further instruments and to take such further actions as may be necessary or desirable to carry out the purposes and intent of this 33. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". If a user or application submits more than 10 requests per second, further requests from the IP address(es) may be limited for a brief period. Please disable your ad-blocker and refresh. Incyte Corporation (INCY): INCY was already a 1.67M share stake in their first 13F filing in Q2 2003. Despite the uncertainty surrounding BeiGene, the company has developed into a fully integrated global biotechnology company with operations in China, the United States, Europe, and Australia. Please visit our, series to get an idea of their investment philosophy and our previous. The top three positions are Seagen, BeiGene, and Incyte Corporation and they add up to almost ~64% of the portfolio. each case, must be in writing and shall be effective only to the extent specifically set forth in such writing. (g)Delays or Omissions. Broker-Dealer(s): Goldman, Sachs & Co., . Notices shall be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin& Hachigian, LLP. Amarin Corp plc (AMRN): The original AMRN stake was built in Q3 2016 at prices between ~$2.15 and ~$3.15. H1 2018 saw the stake built from ~3.8M shares to ~12M shares at prices between ~$100 and ~$215. In this respect, the Company shall give the Observer copies of all notices, minutes, consents, and other materials that it provides to its directors at The Baker Brothers Entities nominated Fuchs as one of eight nominees to the board of directors at AnorMED, Inc. and, it can be inferred, given the timing, that Fuchs was also appointed by the Baker Brothers Entities to the Mirati The increase happened at ~$72 per share. Q1 2016 saw another ~20% stake increase at prices between ~$65 and ~$100. Blue Sky Digital Outdoor Advertising Fund Fund Data, Sarasin Ie Global Equity Opportunities (Usd) Fund Data, Themelios Ventures Ii-A, L.P. Fund Data. [Remainder of page intentionally left blank]. Get the full list, Morningstar Institutional Equity Research. Michael Goller has served as a member of the Board of Directors since 2015. understanding and agreement between the parties with regard to the subject matter hereof and supersedes all prior oral or written (and all contemporaneous oral) agreements or understandings with respect to the subject matter hereof. 212-339-5600. Active, Closed, This describes the type of investor this organization is (e.g. {"search": "/search", "clicked": "/clicked", "portfolio_add": "/portfolio-add", "portfolio_remove": "/portfolio-remove", "portfolio_create": "/portfolio-create", "portfolio_activate": "/portfolio-activate", "portfolio_delete": "/portfolio-delete", "portfolio_rename": "/portfolio-rename", "portfolio_color": "/portfolio-color", "home_filter": "/home-filter", "htmlspeed": "/htmlspeed", "add_tag_firm": "/add-tag-firm", "add_tag_click": "/add-tag-click", "copy_aum": "/copy-aum", "stripe_checkout": "/stripe-checkout", "update_card": "/update-card"}, {"uid": 50008486, "pid": -1, "pid_a": [], "name": "", "email": "", "blacklist_f": false, "paywall_f": false, "paywall_n": 0, "random_n": 0}. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. Note: Baker Brothers controls ~6% of the business. Youre viewing 5 of 7 investments. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. Analytical cookies are used to understand how visitors interact with the website. 12b-2 under the Securities Exchange Act of 1934, as amended. email address below and choose 'Submit'. There was a ~10% stake increase in Q1 2021 at prices between ~$268 and ~$380. Shares started trading at ~$18 and currently goes for $27.21. Last two quarters have seen minor increases. (d)Common Stock means shares of the Companys Common Stock, par specifically enforced against each of the parties hereto in any court of competent jurisdiction. Performance & security by Cloudflare. This quarter also saw a minor ~4% trimming. Major activity in the last decade follows. Since then, the activity has been minor. You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. Q3 2015 saw a ~30% stake increase at prices between ~$105 and ~$130. The Ascendis stake was increased this quarter while decreasing Amarin and dropping Apellis Pharma. Felix Baker '91, PhD '98. I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. (j)Amendments and Waivers. There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. Updated on November 23rd, 2022 by Nikolaos Sismanis. Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). The provisions of this Agreement may be amended at any time and from time to It is a very long-term stake that has been in the portfolio for over fifteen years. No delay or omission to The rest of the stakes are very small. validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. Mr. Goller serves as a Partner of Baker Brothers Investments, a fund management company focused on long-term investments in life-sciences companies. This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. Shares started trading at ~$49 and currently goes for $13.27. Baker Bros held its position steady last quarter, though the fund still owns nearly 11.4% of the company. Phone: 212-339-5600. The stake goes back to funding rounds prior to their IPO last September. Instead, they emphasize that focusing on specific companies, which they can analyze and understand deeply and place concentrated positions in their securities, can generate superior returns over the long term. 151.252.56.27 With respect to the Observer, the Companys obligations under this Section2(c) are contingent upon such Observers (x)entering into a confidentiality agreement with the Company in a form that is reasonably acceptable to the Pharmaceutical, a company in which the Baker Brothers Entities have been investor s since March 2006. I am not receiving compensation for it (other than from Seeking Alpha). As Chicago's biotech ecosystem continues to expand . Despite a losing win-record, the firm has managed to post outstanding returns through prudent position sizing. Baker Brothers 13F portfolio value remained almost steady at $22.77B this quarter. BioCryst Pharmaceuticals (BCRX): BCRX is a very long-term stake that has been in the portfolio since 2004. Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. removed or otherwise fails to become or ceases to be a director for any reason, the Company shall cause the vacancy to be filled by the election or appointment of another Investor Designee nominated by the Investor as soon as reasonably practicable (k)Jurisdiction. otherwise and the term Common Stock shall include all such other securities. To allow for equitable access to all users, SEC reserves the right to limit requests originating from undeclared automated tools. Note: We do not offer technical support for developing or debugging scripted downloading processes. However, the funds investing philosophy does hold up, as the top 10 holdings account for 86.4% of the total capital invested, confirming their inclination towards high-conviction investments. Companys shares are listed, the Bylaws or any policy, or guidelines previously approved by the Board of Directors, provided that a direct or indirect purpose of any such policy or guideline is not to obstruct the Investors right to Shares started trading at ~$24 and currently goes for ~$246. All notices required or permitted under this Agreement must be in writing and sent to the THIS AMENDED AND RESTATED NOMINATING AGREEMENT (this Agreement), dated as of April22, 2021, by and among TScan Get the full list, Massachusetts Institute of Technology Long-Term Disability Plan, Youre viewing 5 of 11 limited partners. other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. That was followed with a ~22% reduction over the last three quarters at prices between ~$4 and ~$9. Last major activity was a ~60% stake increase in 2017 at prices between ~$80 and ~$95. BeiGene Limited (BGNE): The large (top three) 18.60% BGNE stake has been in the portfolio since their US listing in Q1 2016. Baker Brothers Life Sciences, L.P. is one of the larger private funds with 13.9 billion in assets. Click to reveal for so long as they remain in force, the Voting Agreement (as defined in the Purchase Agreement) and that certain letter agreement, dated as of January15, 2021, by and among the Company and the Investor, constitutes the full and entire to see more advanced email alert options such as selecting any type of Nominating Agreement as of the date first above written. The Baker brothers have built a truly special hedge fund. To explore Baker Brothers Life Sciencess full profile, request access. NEW YORK, NY offering of its Common Stock under the Securities Act of 1933, as amended. Common Stock, the Company shallsupport the nomination of, and cause the Board of Directors (or the nominating committee thereof), subject to the requirements of fiduciary duties under applicable law, to include in the slate of nominees The current estimated net worth of Kodiak Sciences Inc's Director, Felix Baker, is estimated to be about $16.52B . I wrote this article myself, and it expresses my own opinions. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. They add up to ~73% of the portfolio. the Investor pursuant to the Purchase Agreement, or such number of shares of Common Stock (whether voting or non-voting) issued upon conversion of such number of shares of Series C Preferred (in either case, (h)Counterparts. Brothers Julian and Felix Baker have earned their guru status on Wall Street, having delivered an exceptional track record of annualized returns over the years. or to simply have an email sent to you whenever we receive a new Note: Baker Brothers controls ~10% of Madrigal Sciences. Last major activity was in Q4 2018 when there was a ~40% stake increase at prices between ~$14 and ~$22. Note: Baker Brothers controls ~29% of the business. The fund owns around 16.3% of the company, with a market cap of $23 billion. Edit Lists Featuring This Company Section. Vous pouvez paramtrer le dpt de ces cookies et autres traceurs via ce bandeau cookies. Form D contains basic information about the offering and the company. After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Brothers Life Sciences Capital, L.P. and (ii) Life Sciences, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I directly held by Life Sciences, a There was a marginal increase last quarter. BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. N/A BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL, L.P. GENERAL PARTNER OF THE GENERAL PARTNER BAKER BROTHERS LIFE SCIENCES CAPITAL (GP), LLC. I have no business relationship with any company whose stock is mentioned in this article. The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. Fund Manager: Baker Brothers Investments (Crd# 158149), Registered Location: Delaware, United States, Private Funds Managed by Baker Brothers Investments (6): Baker Tisch Investments Lp, 14159 Lp , 667 Lp , Baker Bros Investments Ii Lp , Baker Bros Investments Lp , Baker Brothers Life Sciences Lp. The position is now at 1.23% of the portfolio. Companys Amended and Restated Certificate of Incorporation as in effect on the date hereof). Ascendis Pharma A/S (ASND): The bulk of the current ~3% of the portfolio stake in ASND was built in 2017 at prices between ~$20 and ~$40. Baker Bros Advisors was founded in 2000 and is based in New York City. A privately owned hedge fund sponsor. The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. Last major activity in MRTX was a ~50% selling in Q3 2019 at prices between ~$76 and ~$106. This is a profile preview from the PitchBook Platform. 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